2018

• “Inhibition of FAD-dependent lysine-specific demethylases by chiral polyamine analogues”
  Naoki Umezawa, Kasumi Tsuji, Shin Sato, Masaki Kikuchi, Hisami Watanabe, Yuhei Horai, Masashi Yamaguchi, Yosuke Hisamatsu, Takashi Umehara, Tsunehiko Higuchi
  RSC Adv. 2018, 8, 36895-36902.
• “Design and synthesis of a 4-aminoquinoline-based molecular tweezer that recognizes protoporphyrin IX and iron(III) protoporphyrin IX and its application as a supramolecular photosensitizer”
  Yosuke Hisamatsu, Naoki Umezawa, Hirokazu Yagi, Koichi Kato, Tsunehiko Higuchi
  Chem. Sci. 2018, 9(38), 7455-7467.
  Inside back cover と HOT article collection に選定されました．
• “Distinct modulation of group I ribozyme activity among stereoisomers of a synthetic pentamine with structural constraints”
  Mst A Gulshan, Kasumi Tsuji, Shigeyoshi Matsumura, Tsunehiko Higuchi, Naoki Umezawa, Yoshiya Ikawa
  Biochem. Biophys. Res. Commun. 2018, 504(4), 698-703.
• “Comparative study of polyethylene polyamines as activator molecules for a structurally unstable group I ribozyme”
  Mst. Ara Gulshan, Shigeyoshi Matsumura, Tsunehiko Higuchi, Naoki Umezawa, Yoshiya Ikawa
  Biosci. Biotechnol. Biochem., 2018, 82(8), 1404-1407.
• “Branched-chain polyamine found in hyperthermophiles induces unique temperature-dependent structural changes in genome-size DNA”
  Takashi Nishio, Yuko Yoshikawa, Wakao Fukuda, Naoki Umezawa, Tsunehiko Higuchi,Shinsuke Fujiwara, Tadayuki Imanaka, Kenichi Yoshikawa
  ChemPhysChem, 2018, 19, 1-7.
• “Biogenic triamine and tetraamine activate core catalytic ability of Tetrahymena group I ribozyme in the absence of its large activator module”
  Mst Ara Gulshan, Md. Motiar Rahman, Shigeyoshi Matsumura, Tsunehiko Higuchi, Naoki Umezawa, Yoshiya Ikawa
  Biochem. Biophys. Res. Commun., 2018, 496, 594-600.
• “Potent antimalarial activity of two arenes linked with triamine designed to have multiple interactions with heme”
  Yosuke Sakata, Kosuke Yabunaka, Yuko Kobayashi, Hirohisa Omiya, Naoki Umezawa, Hye-Sook Kim, Yusuke Wataya, Yoshimi Tomita, Yosuke Hisamatsu, Nobuki Kato, Hirokazu Yagi, Tadashi Satoh, Koichi Kato, Haruto Ishikawa, Tsunehiko Higuchi
  ACS Med. Chem. Lett. 2018, 9(10), 980-985.